Developing a marker of exposure to xenoestrogen mixtures in human serum.

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Developing a marker of exposure to xenoestrogen mixtures in human serum.

It has been hypothesized that environmental estrogens may play a role in the increasing incidence of breast cancer, testicular cancer, and other problems of the reproductive system. While a single causal agent can be identified in cases in which humans have had occupational exposures, wildlife showing signs of reproductive damage have usually been exposed to a combination of endocrine disruptor...

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Xenoestrogens (XEs) are chemicals derived from a variety of natural and anthropogenic sources that can interfere with endogenous estrogens by either mimicking or blocking their responses via non-genomic and/or genomic signaling mechanisms. Disruption of estrogens' actions through the less-studied non-genomic pathway can alter such functional end points as cell proliferation, peptide hormone rel...

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ژورنال

عنوان ژورنال: Environmental Health Perspectives

سال: 1997

ISSN: 0091-6765,1552-9924

DOI: 10.1289/ehp.97105s3647